James Romberger was born in Port Jefferson, New York. He studied art at the School of Visual Arts and Columbia University. In 1984, Romberger and his partner, the punk musician and artist Marguerite Van Cook, curated pioneering group exhibitions at downtown nightclubs and galleries, including the survey show The East Village Look at Danceteria, the influential stencil show Hit and Run at The Magic Gallery, and the legendary Acid Test at Sensory Evolution. The pair then opened their installation gallery Ground Zero, where they mounted their own early solo exhibits and presented noted shows and installations by the East Village painters Christof Kohlhofer, Peggy Cyphers, Edward Brezinski and the late David Wojnarowicz; and the graffiti masters Sharp, Delta and the late Phase 2. Subsequently, Romberger exhibited his pastel drawings with the venerable Grace Borgenicht Gallery on NYC's 57th Street, and at the Gracie Mansion Gallery in Chelsea.
With Wojnarowicz and Van Cook, Romberger produced “7 Miles a Second,” the acclaimed classic graphic novel based on Wojnarowicz's life. This book began in collaboration with Wojnarowicz in 1986, but it had to be completed from the writer's journals after his untimely 1992 death of AIDS. It was first published by DC Comics' Vertigo imprint in 1996, and has since been reprinted in several languages. In 2011, DC/Vertigo published Aaron and Ahmed, a graphic novel done in collaboration with MacArthur fellow Jay Cantor. In 2014, Fantagraphics Books published The Late Child, Van Cook's generational graphic memoir with drawings by Romberger. Romberger was nominated for an Eisner award for Best Single Issue" for his comic book Post York (2012), which was recently expanded into a full graphic novel and published by Dark Horse Comics in 2021.
Romberger has written on comics, television and film for magazines and websites, including Publisher's Weekly, Aperture, LAAB, Comics Journal and Comics Beat; and taught art at Parsons/The New School, Marywood University and Hunter College. Romberger's electric career spans teaching, magazines, museums, and now NFTs, where he grapples with the symbolism and meaning behind religious iconography in the modern era.