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Erbstatin Analog, methyl 2,5-dihydroxycinnamate, is a stable analog of erbstatin, an inhibitor of EGFR (epidermal growth factor receptor)-associated tyrosine kinase. This erbstatin analog is described to be approximately four times more stable than erbstatin in calf serum. Inhibition of EGFR-associated tyrosine kinase by erbstatin analog in EGFR-overexpressing NIH3T3 cells blocked phenotypic changes in the cells mediated through EGFR activity and delayed EGF-induced DNA synthesis, suggesting use of erbstatin analog as a modifier of EGFR-related malignant phenotypic changes of cells. Erbstatin analog is demonstrated to inhibit autophosphorylation of EGFR and the parent compound is described to inhibit autophosphorylation of the oncogene product p60src in A431 cells. Inhibition of thrombin- and thapsigargin- (sc-24017) induced actin polymerization by erbstatin analog is also described, mediated through inhibition of tyrosine kinases and inhibitory towards store-mediated Ca2+ entry. Erbstatin analog has been further employed as a general inhibitor of tyrosine kinases to identify their activity in various biological processes.
You can become a part of something greater than yourself with us.
Project "a Chance for Eternity" presents collections of 212 main geroprotectors ("A geroprotector is a senotherapeutic that aims to affect the root cause of aging and age-related diseases, and thus prolong the life span" - Wikipedia). One and/or each of these geroprotectors may become the most important for canceling aging and age-related diseases in the close.
We are creating the world's first collection NFTs Geroprotectors and expect its cost will be increased after new research.
Buying items of our NFTs Geroprotectors you may be certain, most ethers will be assets for new research of aging and age-related diseases.
You can become a part of something greater than yourself with us.
Geroprotector #200/212: Erbstatin Analogue
100 소유:
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100 아이템visibility
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Geroprotector #200/212: Erbstatin Analogue
100 소유:
aChanceforEternity
0
view_module
100 아이템visibility
4 조회수- 단가USD 단가수량만료From
- 단가USD 단가수량하한가와의 차이만료From
Erbstatin Analog, methyl 2,5-dihydroxycinnamate, is a stable analog of erbstatin, an inhibitor of EGFR (epidermal growth factor receptor)-associated tyrosine kinase. This erbstatin analog is described to be approximately four times more stable than erbstatin in calf serum. Inhibition of EGFR-associated tyrosine kinase by erbstatin analog in EGFR-overexpressing NIH3T3 cells blocked phenotypic changes in the cells mediated through EGFR activity and delayed EGF-induced DNA synthesis, suggesting use of erbstatin analog as a modifier of EGFR-related malignant phenotypic changes of cells. Erbstatin analog is demonstrated to inhibit autophosphorylation of EGFR and the parent compound is described to inhibit autophosphorylation of the oncogene product p60src in A431 cells. Inhibition of thrombin- and thapsigargin- (sc-24017) induced actin polymerization by erbstatin analog is also described, mediated through inhibition of tyrosine kinases and inhibitory towards store-mediated Ca2+ entry. Erbstatin analog has been further employed as a general inhibitor of tyrosine kinases to identify their activity in various biological processes.
You can become a part of something greater than yourself with us.
Project "a Chance for Eternity" presents collections of 212 main geroprotectors ("A geroprotector is a senotherapeutic that aims to affect the root cause of aging and age-related diseases, and thus prolong the life span" - Wikipedia). One and/or each of these geroprotectors may become the most important for canceling aging and age-related diseases in the close.
We are creating the world's first collection NFTs Geroprotectors and expect its cost will be increased after new research.
Buying items of our NFTs Geroprotectors you may be certain, most ethers will be assets for new research of aging and age-related diseases.
You can become a part of something greater than yourself with us.
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