Guarana has one of the highest caffeine contents of all plants - up to 7% (about twice the concentration of caffeine found in coffee seeds). This plant is native to Amazon, mainly consumed by the Guarani tribe who used its seeds to brew a drink. It is till date taken for weight loss, athletic and mental performance. This plant was used before battles and long voyages to increase resistance to thirst, heat, and fatigue. Guarana has also been used as an ‘alternative drug' to treat diseases like headaches, indigestions, kidney dysfunctions, muscle pain, menstrual cramps, depression, fatigue and used for alleviating cancer-related symptoms.